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R & S
2006

2006

Characterization of kinin receptors in human cultured detrusor smooth muscle cells. Br J Pharmacol. 2007 Jan;150(2):192-9. Epub 2006 Dec 18.

Comparative antagonist pharmacology at the native mouse bradykinin B2 receptor: radioligand binding and smooth muscle contractility studies. Br J Pharmacol. 2007 Feb;150(3):313-20. Epub 2006 Dec 18.

Human and murine macrophages mediate activation of MEN 4901/T-0128: a new promising camptothecin analogue-polysaccharide conjugate. Anticancer Drugs. 2006 Nov;17(10):1119-26

New monocyclic and acyclic hNK-2 antagonists retaining the beta-turn feature. X-ray and molecular modelling studies. Acta Crystallogr B. 2006 Oct;62(Pt 5):889-96. Epub 2006 Sep 18.

MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 2006 Nov 7;549(1-3):140-8. Epub 2006 Aug 26.

Role of sensory neurons in restitution and healing of gastric ulcers. Curr Pharm Des. 2006;12(23):2977-84. Review.

Tachykinin receptors antagonists: from research to clinic. Curr Drug Targets. 2006 Aug;7(8):975-92. Review.

Single and repeated dose pharmacokinetics of dexketoprofen trometamol in patients with impaired liver function. Methods Find Exp Clin Pharmacol. 2006 Jun;28 Suppl A:29-36.

Pharmacokinetics of dexketoprofen trometamol in subjects with mild and moderate chronic renal insufficiency Methods Find Exp Clin Pharmacol. 2006 Jun;28 Suppl A:21-8

Single and repeated dose pharmacokinetics of deketoprofen trometamol in young and elderly subjects Methods Find Exp Clin Pharmacol. 2006 Jun; 28 Suppl A:13-9

Clinical pharmacokinetics of parenteral dexketoprofen trometamol in healthy subjects. Methods Find Exp Clin Pharmacol. 2006 Jun;28 Suppl A:7-12.

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides. J Med Chem. 2006 Jun 15;49(12):3602-13

Tachykinins and tachykinin receptors in the gut, with special reference to NK2 receptors in human. Auton Neurosci. 2006 Jun 30;126-127:232-49. Epub 2006 Apr 17. Review.

Multiple motor effects of ATP and their inhibition by P purinoceptor antagonist, pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid in the small intestine of the guinea-pig. Basic Clin Pharmacol Toxicol. 2006 May;98(5):488-95.

Effects of nebivolol in elderly heart failure patients with or without systolic left ventricular dysfunction: results of the SENIORS echocardiographic substudy. Eur Heart J. 2006 Mar;27(5):562-8. Epub 2006 Jan 27. Erratum in: Eur Heart J. 2006 Jul;27(14):1760.

Fibrinolytic efficacy of Amediplase, Tenecteplase and scu-PA in different external plasma clot lysis models: sensitivity to the inhibitory action of thrombin activatable fibrinolysis inhibitor (TAFI). Thromb Haemost. 2006 Sep;96(3):325-30.

Tachykinins and tachykinin receptors: effects in the genitourinary tract. Life Sci. 2005, 76(8): 835-62.

Effects of angiotensin-converting-enzyme inhibitors in combination with diuretics on blood pressure and renal injury in nitric oxide-deficiency-induced hypertension in rats. Clin Sci (Lond). 2006 Feb;110(2):227-33.

Nationwide efficacy-safety study of nebivolol in mildly hypertensive patients. Am J Ther. 2006 May-Jun;13(3):192-7.

Bradykinin antagonists modified with dipeptide mimetic beta-turn inducers. Bioorg Med Chem Lett. 2006 May 1;16(9):2387-90. Epub 2006 Feb 28.

Nebivolol: a review of its clinical and pharmacological characteristics. Int J Clin Pharmacol Ther. 2006 Aug;44(8):344-57

Efficacy and safety of lercanidipine versus hydrochlorothiazide as add-on to enalapril in diabetic populations with uncontrolled hypertension. J Hypertens. 2006 Jan;24(1):185-92.

Electrochemical detection of tobramycin or gentamicin according to the European Pharmacopoeia analytical Method

J Chromatogr A. 2007 Jan 12; 1139(1):53-6. Epub 2006 Dec 5.

The fragment-approach: An update Drug Discovery Today: Technologies, 2006, Vol. 3 No. 4,: 425-431